The harmonica is a wind instrument (aerophone) that is closely related to the accordion in terms of tone production. It was designed by Christian Friedrich Buschmann in 1821. Instead of using bellows, air is blown or sucked through the openings with the mouth. The air stream causes a tongue to vibrate, which produces a tone. The harmonica is usually alternating in tone; blowing and sucking produce a different tone. The simplest harmonicas are diatonic; these harmonicas only contain notes from one particular major or minor scale. The harmonica is an instrument that is spread all over the world, and it was the first instrument played by people outside the atmosphere (astronaut Wally Schirra during Gemini VI, 1966). The Netherlands also has many harmonica players, some of whom have united. Several presidents of the United States played the harmonica, including Theodore Roosevelt and Ronald Reagan.